GIMP Plugin Registry

This script is meant to cut an image is smaller pieces and save these images automatically based on the size and names of specific layers, images to be used in web layouts.

Other options I found are based on guidelines. This approach has 2 drawbacks for me :  read more »

Save for Web allows to find compromise between minimal file size and acceptable quality of image quickly. While adjusting various settings, you may explore how image quality and file size change. Options to reduce file size of an image include setting compression quality, number or colors, resizing, cropping, Exif information removal, etc.